Publications | Mysite

Joel Christie, C. Merlyn Anthony, Mahalakshmi Harish, Deepti Mudartha, Sheikh Burhan Ud Din Farooqee, Prasanna Venkatraman. The interaction network of the proteasome assembly chaperone PSMD9 regulates proteostasis. FEBS Journal (2023). https://doi.org/10.1111/febs.16948.

Mukund Sudharsan M G, Somavally Dalvi, Prasanna Venkatraman. Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution. Protein Science. 2022; 31( 12):e4515. (PDB ID - 7VXV, 7VXW, 7VY4 and 7VY7)

Saim Wasi Mulla, Prasanna Venkatraman. Novel Nexus with NFκB, β-catenin, and RB1 empowers PSMD10/Gankyrin to counteract TNF-α induced apoptosis establishing its oncogenic role. The International Journal of Biochemistry & Cell Biology, 146, 106209 (2022).

Mukund Sudharsan M G, Prasanna Venkatraman. A crystal form of PSMD10Gankyrin with channels accessible to small molecules. Current Science, 122, 6:674-681 (2022). (PDB ID - 7VO6)

Sreevidya TS, Somavally Dalvi, Prasanna Venkatraman, Satyavani Vemparala. Structural insights on the effects of mutation of a charged binding pocket residue on phosphopeptide binding to 14-3-3zeta Protein. PROTEINS:Structure, Function, and Bioinformatics, 90( 5), 1179- 1189 (2022).

Mukund Sudharsan M G, Rupesh Chikhale, Padma P. Nanaware, Somavally Dalvi, Prasanna Venkatraman. A druggable pocket on PSMD10Gankyrin that can accommodate an interface peptide and doxorubicin. European Journal of Pharmacology, 915, 174718 (2022).

Sheikh Burhan Ud Din Farooqee, Joel Christie, Prasanna Venkatraman, PSMD9 ribosomal protein network maintains nucleolar architecture and WT p53 levels, Biochemical and Biophysical Research Communications, 2021, https://doi.org/10.1016/j.bbrc.2021.05.004.

Arunabha Bose, Kruti Modi, Suchismita Dey, Somavally Dalvi, Prafful Nadkarni, Mukund Sudarshan, Tapas K. Kundu, Prasanna Venkatraman, Sorab N. Dalal, 14–3-3γ prevents centrosome duplication by inhibiting NPM1 function, Genes Cells. 2021, https://doi.org/10.1111/gtc.12848

Mahalakshmi Harish, Prasanna Venkatraman, Evolution of biophysical tools for quantitative protein interactions and drug discovery, Emerging Topics in Life Sciences, 2021. https://doi.org/10.1042/ETLS20200258.

Anshul Budhraja, Sakshi Pandey, Srinivasaraghavan Kannan, Chandra S. Verma, Prasanna Venkatraman, The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus – evolved or yet to evolve, Biochemistry and Biophysics Reports, Volume 25, 2021, https://doi.org/10.1016/j.bbrep.2021.100907.

Prashant Pradhan, Ankit Srivastava, Jasdeep Singh, Banhi Biswas, Akanksha Saini, Ibrar Siddique, Pooja Kumari, Mohd. Asim Khan, Akhilesh Mishra, Pramod Kumar Yadav, Shivani Kumar, Neel Sarovar Bhavesh, Prasanna Venkatraman, Perumal Vivekanandan, Bishwajit Kundu. Prion protein transcription is auto-regulated through dynamic interactions with G-quadruplex motifs in its own promoter. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020.

Akshay S, Basu S, Chakraborty S, Sundararajan R, Venkatraman P. Functional Significance Checking in Noisy Gene Regulatory Networks. International Conference on Principles and Practice of Constraint Programming, 2019.

Indrajit Sahu, Padma Nanaware, Minal Mane, Saim Wasi Mulla, Soumen Roy and Prasanna Venkatraman. Role of a 19S Proteasome Subunit- PSMD10Gankyrin in Neurogenesis of human Neuronal Progenitor Cells. International Journal of Stem Cells, 2019.

Modi K, Dalvi S, Venkatraman P. Two negatively charged invariant residues influence ligand binding and conformational dynamics of 14-3-3ζ. FEBS Letters, 2019.

Harish M, Kannan S, Puttagunta S, Pradhan M, Verma C, Venkatraman P. A novel determinant of PSMD9 PDZ binding guides the evolution of first generation of super binding peptides. Biochemistry, 2019.

T Devanand, P Venkatraman, S Vemparala. Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics. Scientific reports, 2018.

Nikhil Sangith, Kannan Srinivasaraghavan, Indrajit Sahu, Ankita Desai, Spandana Medipally, Arun K Somavarappu, Chandra Verma, Prasanna Venkatraman. Discovery of Novel Interacting Partners of PSMD9 a Proteasomal Chaperone -Role of an Unusual and Versatile PDZ-Domain Motif Interaction and Identification of Putative Functional Modules. Febs Open Bio May 2014.

Sahu I, Sangith N, Ramteke M, Gadre R, Venkatraman P. A novel role for the Proteasomal Chaperone PSMD9 and hnRNPA1 in enhancing I?B? degradation and NF-?B activation - Functional Relevance of predicted PDZ domain-motif interaction. FEBS J. 2014 Apr 10. doi: 10.1111/febs.12814.

Arun Kumar Somavarapu, Satish Balakrishnan, Amit Kumar S Gautam, David S Palmer and Prasanna Venkatraman. Structural Interrogation of Phosphoproteome Identified by Mass Spectrometry Reveals Allowed and Disallowed Regions of Phosphoconformation. BMC Struct Biol. 2014 Mar 11;14(1):9. doi: 10.1186/1472-6807-14-9.

Nanaware P, Ramteke M, Somavarapu AK, Venkatraman P. Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein -Evidence for a common hot spot site at the interface and its functional relevance. Proteins. 2013 Dec 13. doi: 10.1002/prot.24494.

Ramteke MP, Shelke P, Ramamoorthy V, Somavarapu AK, Gautam AK, Nanaware PP, Karanam S, Mukhopadhyay S, Venkatraman P. Identification of a novel ATPase activity in 14-3-3 proteins - Evidence from enzyme kinetics, structure guided modeling and mutagenesis studies. FEBS Lett. 2013 Nov 20. pii: S0014-5793(13)00842-9. doi: 10.1016/j.febslet.2013.11.008

Wadhawan V, Kolhe YA, Sangith N, Gautam AK, Venkatraman P. From Prediction to Experimental Validation-Desmoglein 2 is a Functionally Relevant Substrate of Matriptase in Epithelial Cells and their Reciprocal Relationship is Important for Cell Adhesion. Biochem J. 2012 Jul 11. PMID: 22783993

Singh Gautam AK, Balakrishnan S, Venkatraman P. Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals. PLoS One. 2012;7(4):e34864.